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Article summary:
1. Enterococcus faecalis is a common cause of hospital-associated infections, particularly infective endocarditis, which has high mortality rates.
2. Combination antibiotic therapy is the best treatment option for severe enterococcal infections, but optimal treatment has not been fully elucidated.
3. Ampicillin plus ceftriaxone has emerged as a preferred treatment option, but more research is needed to improve patient outcomes from this high-mortality disease.
Article analysis:
该文章是一篇关于治疗Enterococcus faecalis血流感染和感染性心内膜炎的综述。文章提到了E. faecalis引起的严重高菌量感染，如感染性心内膜炎，需要使用联合抗生素治疗。然而，最佳治疗方案尚未完全阐明。
文章没有明显的偏见或宣传内容。但是，它可能存在一些片面报道和缺失的考虑点。例如，文章没有提到其他可能导致高死亡率的因素，如患者基础疾病、手术并发症等。此外，文章也没有探讨其他可能有效的治疗方案，如药物联合使用的剂量和时机等。
此外，文章提出了一些主张，但缺乏支持这些主张的证据。例如，在讨论抗生素联合治疗时，文章指出氨苄西林加头孢曲松已成为首选治疗方案。然而，并没有提供足够的证据来支持这种观点。
总之，该文章提供了有用的信息和方向来改善E. faecalis感染的治疗方法。然而，在未来的工作中需要更多地考虑其他因素，并进行更全面的研究来支持所提出的主张。
Topics for further research:
Other factors contributing to high mortality rates in E. faecalis infections
Alternative effective treatment options for E. faecalis infections
Evidence supporting the use of ampicillin plus ceftriaxone as the preferred treatment for E. faecalis infections
Limitations or biases in the article's coverage of E. faecalis infections
Future research directions for improving E. faecalis infection treatment
Considerations for dosing and timing of combination drug therapy in E. faecalis infections