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1. Breast cancer is the most common malignancy among women in the western world, and the incidence of clinically observed bilateral breast cancer (BBC) ranges from 1.4% to 11.8%. There is uncertainty in the literature regarding whether developing a contralateral tumor influences the outcome, as some studies suggest poor survival while others report similar survival compared to unilateral disease.

2. Factors such as family history of breast cancer, initial tumor diagnosed at an early age, lobular histology of the first tumor, treatment received for the first tumor, and nulliparity contribute to the risk of developing contralateral breast tumor.

3. The management of patients with BBC is still uncertain. Some reports confirm the efficiency of bilateral mastectomy in managing BBC, while others question its benefit in reducing rates of BBC diagnoses and improving survival rate. Additionally, MRI has shown increased sensitivity for detecting breast cancer compared to conventional methods but its role in screening settings has not yet been outlined.

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