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Amantadine Treatment for People with COVID-19 - ScienceDirect
Source: sciencedirect.com
Article summary:
1. Amantadine may be a viable alternative to reduce the effects of COVID-19, as studies have shown that people with Parkinson's disease who are on amantadine treatment and have tested positive for the coronavirus have not had clinical manifestations of the disease.
2. Amantadine has been used as an antiviral therapy against the influenza A virus, and it is proposed that it could enter the E-channel of the coronavirus preventing the release of the viral nucleus into the cell.
3. Amantadine is well tolerated by the digestive system and has a moderate diuretic effect, but laboratory tests should be repeated one or two weeks after starting treatment in order to adjust doses if necessary.
Article analysis:
The article “Amantadine Treatment for People with COVID-19” provides an overview of how amantadine may be used to mitigate symptoms caused by SARS-Cov-2, which causes COVID-19. The article presents evidence from various studies that suggest amantadine may reduce viral load and prevent symptoms in those infected with COVID-19.
The article appears to be reliable and trustworthy overall, as it cites multiple sources for its claims and provides detailed explanations for its conclusions. It also acknowledges potential risks associated with using amantadine, such as overdose risk and interactions with other medications.
However, there are some points of consideration that are missing from this article. For example, while it mentions that amantadine has been used to treat influenza A virus in adults since 1976, it does not mention any potential side effects or long term effects associated with taking this medication over a long period of time. Additionally, while it mentions that laboratory tests should be repeated one or two weeks after starting treatment in order to adjust doses if necessary, it does not provide any information about what these tests should measure or how they should be interpreted.
In conclusion, this article appears to be reliable overall but could benefit from providing more information about potential side effects and long term effects associated with taking amantadine over a long period of time as well as more details about what laboratory tests should measure when adjusting doses if necessary.