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Article summary:

1. Stress hyperglycemia is associated with poor prognosis in patients experiencing acute ischemic stroke (AIS).

2. This study evaluated the impact of stress hyperglycemia on the risk of early neurological deterioration (END) after intravenous administration of recombinant tissue-type plasminogen activator (IV-rtPA) in AIS patients.

3. The results showed that a higher stress hyperglycemia ratio (SHR) predicted that patients with severe stress hyperglycemia had higher risks of END and poor functional outcome at discharge after IV-rtPA.

Article analysis:

The article is generally reliable and trustworthy, as it provides evidence from a large sample size of 798 consecutive patients treated with IV-rtPA, and the authors have adjusted for confounders in their analysis. The article also presents both sides of the argument equally, noting potential risks and providing evidence to support its claims. However, there are some potential biases that should be noted. For example, the study only included Chinese patients, which may limit its generalizability to other populations. Additionally, the study did not explore any counterarguments or alternative explanations for its findings, which could provide further insight into the topic. Finally, there is no mention of any potential conflicts of interest or promotional content in the article, which could be important considerations when evaluating its trustworthiness and reliability.