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Article analysis:

The article is generally reliable and trustworthy as it provides a comprehensive overview of the role of the PI3K/AKT/mTOR signaling pathway in ovarian cancer, including its importance in tumorigenesis, proliferation and progression, as well as pre-clinical and clinical experience with several PI3K/AKT/mTOR pathway inhibitors. The article also cites relevant studies to support its claims.

However, there are some potential biases that should be noted. For example, the article does not explore any counterarguments or alternative perspectives on the use of PI3K/AKT/mTOR pathway inhibitors for treating ovarian cancer. Additionally, while it mentions possible risks associated with these treatments, it does not provide any detailed information about them or discuss how they can be managed or minimized. Furthermore, while it provides a comprehensive overview of pre-clinical and clinical experience with several PI3K/AKT/mTOR pathway inhibitors in OC, it does not provide any information about other treatments that may be available for treating ovarian cancer. Finally, while it mentions that there is no FDA approved inhibitor available for treating OC yet, it does not provide any information about ongoing research into developing such treatments or when they may become available.