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Inhaled sedation in the intensive care unit - PubMed
Source: pubmed-ncbi-nlm-nih-gov-443.webvpn.bjmu.edu.cn
May be slightly imbalanced

Article summary:

1. Inhaled sedation with halogenated agents like isoflurane or sevoflurane is now feasible in ICU patients through dedicated vaporisers and scavenging systems.

2. Isoflurane and sevoflurane have ideal pharmacological properties that allow efficient, well-tolerated, and titratable light-to-deep sedation, and may have clinical benefits relevant to ICU patients.

3. The article summarizes the pharmacological basis and practical aspects of inhaled ICU sedation, reviews available evidence supporting it as a viable alternative to intravenous sedation, and discusses remaining areas of uncertainty and future perspectives of development.

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