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1. Dilated cardiomyopathy is characterized by left ventricular or biventricular dilatation or systolic dysfunction, and can be caused by genetic factors (primary dilated cardiomyopathy) or acquired factors (secondary dilated cardiomyopathy).

2. Acquired factors that can contribute to dilated cardiomyopathy include infections, toxins, cancer treatment, endocrinopathies, pregnancy, tachyarrhythmias, and immune-mediated diseases.

3. The diagnostic tests and therapeutic approach for dilated cardiomyopathy should consider both genetic and acquired factors, and future treatments may focus on repairing or replacing gene mutations or targeting specific inflammatory, metabolic, or pro-fibrotic drivers of the disease.

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