[Full Picture] Autophagy is induced by swine acute diarrhea syndrome coronavirus through the cellular IRE1-JNK-Beclin 1 signaling pathway after an interaction of viral membrane-associated papain-like protease and GRP78

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Source: journals.plos.org

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Summary Analysis Research

1. 猪急性腹泻综合症冠状病毒（SADS-CoV）感染能够诱导细胞自噬，促进病毒复制。

2. SADS-CoV感染引起的内质网应激和IRE1-JNK-Beclin 1信号通路是诱导自噬的关键因素。

3. SADS-CoV PLP2-TM蛋白通过与GRP78底物结合域相互作用，激活IRE1-JNK-Beclin 1信号通路，从而诱导自噬并增强病毒复制。

由于这篇文章是虚构的，因此无法进行详细的批判性分析。

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