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1. Dual-Specificity Phosphatase 3 (DUSP3) deletion protects female mice from endotoxemia-induced and polymicrobial-induced septic shock, but not male mice.

2. The study was conducted by researchers from the Inflammation Research Center at VIB and the Department of Biomedical Molecular Biology at Ghent University in Belgium.

3. The findings suggest that DUSP3 may play a role in the sex-specific response to septic shock, highlighting the importance of considering gender differences in sepsis research and treatment.

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