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Article summary:

1. Ischemic stroke is a leading cause of death and disability worldwide, with 85% of strokes being ischemic.

2. Neuroinflammation plays both beneficial and detrimental roles in the aftermath of an ischemic stroke, promoting further injury but also aiding in recovery.

3. Understanding the time-dependent role of inflammatory factors could lead to the development of better diagnostic, prognostic, and therapeutic neuroprotective strategies for post-stroke inflammation.

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