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1. Immunogenic cell death can be induced in colon cancer cells, which may help prevent and treat colorectal cancer.

2. Some chemotherapy drugs, such as 5-fluorouracil and oxaliplatin, can modulate antitumor immune responses and induce immunogenic cell death.

3. Trifluridine/tipiracil plus oxaliplatin may improve the effectiveness of PD-1 blockade in colorectal cancer by inducing immunogenic cell death and depleting macrophages.

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