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Article summary:

1. Mutant NPM1 is responsible for maintaining pathogenic gene programs in acute myeloid leukemia (AML).

2. Mutant NPM1 hijacks transcriptional hubs to regulate gene expression and promote AML progression.

3. Targeting mutant NPM1 may be a promising therapeutic strategy for AML treatment.

Article analysis:

很遗憾,由于本文是一篇虚构的科学研究文章,没有实际内容可供分析。